Serine/threonine-protein kinase OSR1

Definition:

Phosphorylates RELL1, RELL2 and RELT. Phosphorylates PAK1. Phosphorylates PLSCR1 in the presence of RELT.

References:

[1]. John K Cusick, et al. Identification of PLSCR1 as a protein that interacts with RELT family members. Mol Cell Biochem. 2012 Mar;362(1-2):55-63. [Content Brief]

[2]. Wei Chen, et al. Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily. J Biol Chem. 2004 Mar 19;279(12):11129-36. [Content Brief]

[3]. Pachai Moua, et al. RELT family members activate p38 and induce apoptosis by a mechanism distinct from TNFR1. Biochem Biophys Res Commun. 2017 Sep 9;491(1):25-32. [Content Brief]

[4]. John K Cusick, et al. Identification of RELT homologues that associate with RELT and are phosphorylated by OSR1. Biochem Biophys Res Commun. 2006 Feb 10;340(2):535-43. [Content Brief]

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