Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

Definition:

May regulate MCM3AP phosphorylation through phosphatase recruitment (By similarity). May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells (By similarity).

References:

[1]. Kazuhiro Katayama, et al. Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function. Cancer Lett. 2014 Apr 1;345(1):124-31. [Content Brief]

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