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  2. Serine/threonine-protein phosphatase 4 regulatory subunit 3A

Serine/threonine-protein phosphatase 4 regulatory subunit 3A

Definition:

Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair.

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