U6 snRNA-associated Sm-like protein LSm5

Definition:

Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

References:

[1]. Karl Bertram, et al. Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. Cell. 2017 Aug 10;170(4):701-713.e11. [Content Brief]

[2]. T Achsel, et al. A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. EMBO J. 1999 Oct 15;18(20):5789-802. [Content Brief]

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