Zinc finger CW-type PWWP domain protein 2

Definition:

Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0.

References:

[1]. Yanli Liu, et al. Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins. J Biol Chem. 2016 Apr 22;291(17):9000-13. [Content Brief]

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