1. GPCR/G Protein
    Neuronal Signaling
  2. mAChR
  3. Biperiden Hydrochloride

Biperiden Hydrochloride (Synonyms: KL 373 (Hydrochloride))

Cat. No.: HY-13204
Handling Instructions

Biperiden Hydrochloride (KL 373 Hydrochloride) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker.

For research use only. We do not sell to patients.

Biperiden Hydrochloride Chemical Structure

Biperiden Hydrochloride Chemical Structure

CAS No. : 1235-82-1

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 198 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 198 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 180 In-stock
Estimated Time of Arrival: December 31
500 mg USD 720 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Other Forms of Biperiden Hydrochloride:

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Description

Biperiden Hydrochloride (KL 373 Hydrochloride) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. Target: M1 receptors Biperiden is an antiparkinsonian agent of the anticholinergic type. It is used for the adjunctive treatment of all forms of Parkinson's disease (postencephalitic, idiopathic, and arteriosclerotic)[1]. Biperiden has an atropine-like blocking effect on all peripheral structures which are parasympathetic-innervate. It also has a prominent central blocking effect on M1 receptors [2]. Biperiden (0.11 mg/kg), benactyzine (0.3 mg/kg),caramiphen (10 mg/kg), procyclidine (3 mg/kg), and trihexyphenidyl (0.12 mg/kg) separately and each in combination with physostigmine (0.1 mg/kg) is to make a comparative assessment of potential cognitive effects. The results showed that benactyzine, caramiphen, and trihexyphenidyl reduced rats' innate preference for novelty, whereas biperiden and procyclidine did not [3]. Clinical indications: parkinsonism FDA Approved Date: Toxicity: Drowsiness; vertigo; headache; dizziness

Clinical Trial
Molecular Weight

347.92

Formula

C₂₁H₃₀ClNO

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (57.48 mM; Need ultrasonic)

H2O : 5 mg/mL (14.37 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8742 mL 14.3711 mL 28.7422 mL
5 mM 0.5748 mL 2.8742 mL 5.7484 mL
10 mM 0.2874 mL 1.4371 mL 2.8742 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Biperiden Hydrochloride
Cat. No.:
HY-13204
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