2. Gene
  3. CEL - carboxyl ester lipase Gene

CEL - carboxyl ester lipase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BAL; FAP; BSDL; BSSL; CELL; FAPP; LIPA; CEase; MODY8

Gene ID: 1056 | Gene type: protein coding

About CEL

Summary

The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in Cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with Cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008]

CEL Products(1)

mRNA Protein Name
NM_001807.6 NP_001798.3 bile salt-activated lipase precursor
Protein Preferred Names Protein Names

bile salt-activated lipase

bucelipase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-162407 I-As-1 Inhibitor / Unkown
HY-N0278 Anemonin Inhibitor / Unkown
HY-RS02454 CEL Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CEL NCBI
Macaca fascicularis CEL NCBI
Canis lupus familiaris CEL NCBI
Mus musculus CEL NCBI
Susscrofa domestica CEL NCBI
Rattus norvegicus CEL NCBI
Macaca mulatta CEL NCBI