Anemonin (Synonyms: Pulsatilla camphor; Anemonine; trans-Anemonin)

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Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases.

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Anemonin Chemical Structure

CAS No. : 508-44-1

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Description	Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases^[1]^[2].
Molecular Weight	192.17
Formula	C₁₀H₈O₄
CAS No.	508-44-1
SMILES	O=C1C=C[C@@]2([C@]3(CC2)C=CC(O3)=O)O1
Structure Classification	Others
Initial Source	Plants Ranunculaceae Clematis crassifolia Benth.
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Jiang L, et al. Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ. Chin Med. 2022 Mar 28;17(1):39. [Content Brief] [2]. Lee TH, et al. Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor. J Ethnopharmacol. 2008 Mar 28;116(3):518-27. [Content Brief]

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anemonin508-44-1Pulsatilla camphor Anemonine trans-AnemoninPKCNO SynthaseProtein kinase CNitric oxide synthasesNOSHT-29 celsinflammationulcerative colitisInhibitorinhibitorinhibit

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Anemonin (Synonyms: Pulsatilla camphor; Anemonine; trans-Anemonin)

Anemonin Related Antibodies

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Biological Activity

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