NPTXR - neuronal pentraxin receptor Gene

Homo sapiens

Also known as NPR

Gene ID: 23467 | Gene type: protein coding

About NPTXR

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:38,818,452-38,844,028 (from NCBI)

This gene has 1 transcript (splice variant), 195 orthologues and 8 paralogues. Biased expression in brain (RPKM 73.3), heart (RPKM 6.6) and 3 other tissues.

Summary

This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008]

NPTXR Products(1)

mRNA	Protein	Name
NM_014293.4	NP_055108.2	neuronal pentraxin receptor

NPTXR Protein Structure

Pentaxin

0
100
200
300
400
500 a.a.

Protein Preferred Names

Protein Names

neuronal pentraxin receptor

Recombinant NPTXR Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76522	NPTXR Protein, Human (HEK293, His)	O95502 (A24-A500)	≥95%

Related Diseases

Diseases

Alias

Febrile Seizures, Familial, 6

FEB6	Familial Febrile Seizures 6
Convulsions, Familial Febrile, 6	Familial Febrile Convulsions 6
Febrile Convulsions, Familial, 6

Spinocerebellar Ataxia 23

Spinocerebellar Ataxia Type 23	SCA23
Ataxia, Spinocerebellar, Type 23

Mirror Movements 1

Congenital Mirror Movement Disorder	Bimanual Synergia
Congenital Mirror Movements	Familial Congenital Controlateral Synkinesia
Familial Congenital Mirror Movements	Hereditary Congenital Controlateral Synkinesia
Hereditary Congenital Mirror Movements	Isolated Congenital Controlateral Synkinesia
Isolated Congenital Mirror Movements	Mirror Movements
MRMV1	Mirror Movements 1 And/Or Agenesis Of The Corpus Callosum
Mirror Movements, Congenital	Bimanual Synkinesis
Cmm	Mirror Movements, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09507	NPTXR Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NPTXR	MGD	MGI:1920590
Rattus norvegicus	NPTXR	RGD	RGD:628898
Macaca mulatta	NPTXR	VGNC	VGNC:97108
Bos taurus	NPTXR	VGNC	VGNC:32220
Others	NPTXR	NCBI

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