NPTXR Protein, Human (HEK293, His)

The NPTXR protein may mediate synaptic processes, suggesting its involvement in synaptic material uptake during remodeling or AMPA receptor clustering at specific excitatory synapses. These effects suggest that NPTXR dynamically regulates synaptic structure and function. NPTXR Protein, Human (HEK293, His) is the recombinant human-derived NPTXR protein, expressed by HEK293 , with N-His labeled tag. The total length of NPTXR Protein, Human (HEK293, His) is 477 a.a., with molecular weight of 55-75 KDa.

NPTXR Protein emerges as a potential mediator in synaptic processes, suggesting its involvement in either the uptake of synaptic material during synapse remodeling or the synaptic clustering of AMPA glutamate receptors at specific excitatory synapses. These roles implicate NPTXR in the dynamic regulation of synaptic structure and function. Elucidating the precise mechanisms through which NPTXR participates in synapse remodeling and AMPA receptor clustering could offer valuable insights into its contributions to synaptic plasticity and neurotransmission. Further exploration of NPTXR's functions may deepen our understanding of its specific implications in various neuronal processes and its potential significance in maintaining synaptic integrity and functionality.

Human

HEK293

N-10*His

O95502 (A24-A500)

23467  [NCBI]

ASVPLAASPARALPGGADNASVASGAAASPGPQRSLSALHGAGGSAGPPALPGAPAASAHPLPPGPLFSRFLCTPLAAACPSGAQQGDAAGAAPGEREELLLLQSTAEQLRQTALQQEARIRADQDTIRELTGKLGRCESGLPRGLQGAGPRRDTMADGPWDSPALILELEDAVRALRDRIDRLEQELPARVNLSAAPAPVSAVPTGLHSKMDQLEGQLLAQVLALEKERVALSHSSRRQRQEVEKELDVLQGRVAELEHGSSAYSPPDAFKISIPIRNNYMYARVRKALPELYAFTACMWLRSRSSGTGQGTPFSYSVPGQANEIVLLEAGHEPMELLINDKVAQLPLSLKDNGWHHICIAWTTRDGLWSAYQDGELQGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTAPLLGNVLPWEDKLVEAFGGATKAAFDVCKGRAKA

Approximately 55-75 kDa due to the glycosylation

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.