DUXA - double homeobox A Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 503835

About DUXA

Cytogenetic location: 19q13.43 Genomic coordinates (GRCh38): 19:57,154,021-57,167,485 (from NCBI)

This gene has 1 transcript (splice variant), 45 orthologues and 50 paralogues. Low expression observed in reference dataset.

Summary

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 Amino acids referred to as the homeodomain. This gene is a member of the DUXA homeobox gene family. Evidence of mRNA expression has not yet been found for this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of this gene in the germ line or embryonic cells. [provided by RefSeq, Jul 2008]

DUXA Products (1)

mRNA Protein Name
NM_001012729.2 NP_001012747.1 double homeobox protein A

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DUXA Protein Structure

Homeobox

Homeobox: Homeobox domain (16 - 70)

Homeobox

Homeobox: Homeobox domain (102 - 155)

  • 0
  • 100
  • 204 a.a.
Protein Preferred Names Protein Names

double homeobox protein A

Related Diseases

Diseases Alias
Corneal Dystrophy, Posterior Polymorphous, 1

  • Posterior Polymorphous Corneal Dystrophy

  • Ppcd

  • Maumenee Corneal Dystrophy

  • Posterior Polymorphous Corneal Dystrophy 1

  • PPCD1

  • Corneal Dystrophy, Hereditary Polymorphous Posterior

  • Corneal Endothelial Dystrophy 1, Autosomal Dominant

  • Schlichting Dystrophy

  • Ched1

  • Corneal Endothelial Dystrophy 1, Autosomal Dominant, Formerly

  • Ched1, Formerly

  • Hereditary Polymorphus Posterior Corneal Dystrophy

  • Posterior Polymorphous Dystrophy

  • Hereditary Polymorphous Posterior Corneal Dystrophy

  • Dystrophy, Corneal, Posterior Polymorphous

  • Dystrophy, Corneal, Posterior Polymorphous, Type 1

  • Polymorphous Corneal Dystrophy

  • Corneal Endothelial Dystrophy 2
Facioscapulohumeral Muscular Dystrophy 1

  • Facioscapulohumeral Muscular Dystrophy

  • Fshd

  • Landouzy-Dejerine Muscular Dystrophy

  • Muscular Dystrophy, Facioscapulohumeral

  • FSHD1

  • Fshd1a

  • Muscular Dystrophy, Facioscapulohumeral, Type 1a

  • Facioscapulohumeral Muscular Dystrophy Type 1a

  • Fsh Muscular Dystrophy

  • Facioscapulohumeral Muscular Dystrophy 1a

  • Facioscapulohumeral Atrophy

  • Facioscapulohumeral Myopathy

  • Muscular Dystrophy, Facioscapulohumeral, Type 1

  • Facioscapulohumeral Muscular Dystrophy Type 1

  • Landouzy Dejerine Muscular Dystrophy

  • Muscular Dystrophy, Landouzy-Dejerine

  • Fshmd1a

  • Facio-Scapulo-Humeral Dystrophy

  • Facioscapulohumeral Type Progressive Muscular Dystrophy

  • Facioscapuloperoneal Muscular Dystrophy

  • Facioscapulohumeral Dystrophy

  • Fsh Dystrophy

  • Landouzy-Dejerine Dystrophy

  • Landouzy-Dejerine Myopathy

  • Fmd

  • Facioscapulohumeral Muscular Dystrophy-1a

  • Muscular Dystrophy Facioscapulohumeral

  • Dystrophy, Muscular, Facioscapulohumeral

  • Dystrophy, Muscular, Facioscapulohumeral, Type 1

  • Landouzy-Dejerine Disease

  • Landouzy-Déjerine Atrophy

  • Facioscapulohumeral Muscle Dystrophy

  • Fmd - [Facioscapulohumeral Muscular Dystrophy]

  • Fsh - [Facioscapulohumeral Muscular Dystrophy]

  • Fshd - [Facioscapulohumeral Muscular Dystrophy]

  • Landouzy-Déjerine Dystrophy Or Facioscapulohumeral Atrophy

  • Landouzy-Déjérine Muscular Dystrophy
Yaws

  • Frambesia

  • Frambesia Tropica

  • Bouba

  • Frambosie

  • Polypapilloma Tropicum

  • Thymosis

  • Endemic Treponematoses

  • Treponema Pertenue Infection

  • Pian

  • Framboesia

  • Framboesia Tropica

  • Castellani

  • Infection By Treponema Pertenue

  • Parangi

  • Framboesioma

  • Chancre Of Yaws

  • Primary Framboesia

  • Initial Lesions Of Yaws

  • Mother Yaw

  • Initial Framboesia
Bejel

  • Njovera

  • Dichuchwa

  • Nonvenereal Endemic Syphilis

  • Endemic Syphilis

  • Frenga

  • Nonvenereal Syphilis

  • Treponemal Infections

  • Non-Venereal Endemic Syphilis

  • Siti

  • Skerljevo

  • Belesh
Facioscapulohumeral Muscular Dystrophy 2, Digenic

  • Facioscapulohumeral Muscular Dystrophy 2

  • FSHD2

  • Fshd1b

  • Facioscapulohumeral Muscular Dystrophy 1b

  • Fshd2, Digenic

  • Muscular Dystrophy, Facioscapulohumeral, Type 2

  • Muscular Dystrophy, Facioscapulohumeral, Type 1b

  • Fascioscapulohumeral Muscular Dystrophy 2, Digenic

  • Facioscapulohumeral Muscular Dystrophy Type 2

  • Digenic Facioscapulohumeral Muscular Dystrophy

  • Digenic Fshd2

  • Facioscapulohumeral Muscular Dystrophy Type 1b

  • Dystrophy, Muscular, Facioscapulohumeral, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04074 DUXA Human Pre-designed siRNA Set A Pre-designed Set / Unkown