CNTN5 - contactin 5 Gene

Also Known as NB-2; HNB-2s

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 53942

About CNTN5

Cytogenetic location: 11q22.1 Genomic coordinates (GRCh38): 11:99,020,949-100,358,885 (from NCBI)

This gene has 11 transcripts (splice variants), 204 orthologues and 36 paralogues. Biased expression in placenta (RPKM 1.0), thyroid (RPKM 1.0) and 5 other tissues.

Summary

The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

CNTN5 Products (4)

mRNA Protein Name
NM_001243270.2 NP_001230199.1 contactin-5 isoform 1 precursor
NM_001243271.2 NP_001230200.1 contactin-5 isoform 3 precursor
NM_014361.4 NP_055176.1 contactin-5 isoform 1 precursor
NM_175566.2 NP_780775.1 contactin-5 isoform 2 precursor

CNTN5 Protein Structure

I-set

I-set: Immunoglobulin I-set domain (99 - 182)

Ig_2

Ig_2: Immunoglobulin domain (203 - 276)

I-set

I-set: Immunoglobulin I-set domain (307 - 386)

I-set

I-set: Immunoglobulin I-set domain (392 - 475)

I-set

I-set: Immunoglobulin I-set domain (486 - 568)

I-set

I-set: Immunoglobulin I-set domain (574 - 667)

fn3

fn3: Fibronectin type III domain (673 - 760)

fn3

fn3: Fibronectin type III domain (776 - 863)

fn3

fn3: Fibronectin type III domain (878 - 962)

fn3

fn3: Fibronectin type III domain (977 - 1057)

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  • 1100 a.a.
Protein Preferred Names Protein Names

contactin-5

  • neural adhesion molecule

Recombinant CNTN5 Proteins

Cat. No. Product Name Accession Purity
HY-P76841 CNTN5/Contactin-5 Protein, Human (HEK293, His) O94779 (E19-Q1059) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Coffin-Siris Syndrome 6

  • CSS6

  • Coffin-Siris Syndrome, Type 6
Chromosome 3pter-P25 Deletion Syndrome

  • 3p- Syndrome

  • 3p Deletion Syndrome

  • Distal Monosomy 3p

  • Chromosome 3, Monosomy 3p

  • 3p Partial Monosomy Syndrome

  • Chromosome 3, Deletion 3p

  • Chromosome 3p Deletion Syndrome

  • Del Syndrome

  • Deletion 3p

  • Monosomy 3p

  • Partial Monosomy 3p

  • Distal 3p Deletion

  • Monosomy 3pter

  • Telomeric Monosomy 3p

  • Chromosome Deletion Syndrome 3pter-P25
Aleutian Mink Disease

  • Aleutian Disease
Myopathy, Congenital, Compton-North

  • Compton-North Congenital Myopathy

  • MYPCN

  • Congenital Lethal Myopathy, Compton-North Type
Atrial Septal Defect 6

  • ASD6

  • Atrial Heart Septal Defect 6

  • Septal Defect, Atrial, Type 6
Cyclothymic Disorder

  • Cyclothymia

  • Cycloid Personality

  • Cyclothymic Personality

  • Affective Personality Disorder

  • Cyclothymic Personality Disorder

  • Cycloid Personality Disorder
Actinomycosis

  • Actinomycetoma

  • Boil

  • Canaliculitis

  • Actinomycotic Infection

  • Actinomycotic Madura Foot

  • Keratoactinomycosis

  • Furuncle

  • Actinomycotic Mycetema

  • Actinomycotic Mycetoma Of Foot

  • Madura Foot Due To Actinomadura

  • Actinomyces Israeli

  • Actinomycetes

  • Anaerobic Actinomyces Infection

  • Actinomycotic Infection Of Unspecified Site

  • Actinomycosis Nos

  • Actinomycotic Node

  • Actinomyces Infection

  • Actinomycotic Mycetoma

  • Mycetoma Due To Filamentous Bacteria
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02930 CNTN5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20000 Cntn5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26503 Cntn5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CNTN5 RGD RGD:621302
Macaca mulatta CNTN5 VGNC VGNC:71287
Mus musculus CNTN5 MGD MGI:3042287
Canis familiaris CNTN5 VGNC VGNC:39436
Felis catus CNTN5 VGNC VGNC:82001
Others CNTN5 NCBI