DNAH7 - dynein axonemal heavy chain 7 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56171

About DNAH7

Cytogenetic location: 2q32.3 Genomic coordinates (GRCh38): 2:195,737,703-196,068,837 (from NCBI)

This gene has 8 transcripts (splice variants), 238 orthologues and 15 paralogues. Biased expression in testis (RPKM 2.6), thyroid (RPKM 0.9) and 7 other tissues.

Summary

DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008]

DNAH7 Products (1)

mRNA Protein Name
NM_018897.3 NP_061720.2 dynein axonemal heavy chain 7

DNAH7 Protein Structure

DHC_N2

DHC_N2: Dynein heavy chain, N-terminal region 2 (756 - 1166)

AAA_6

AAA_6: Hydrolytic ATP binding site of dynein motor region D1 (1290 - 1517)

AAA_7

AAA_7: P-loop containing dynein motor region D3 (1942 - 2211)

AAA_8

AAA_8: P-loop containing dynein motor region D4 (2304 - 2574)

MT

MT: Microtubule-binding stalk of dynein motor (2587 - 2933)

AAA_9

AAA_9: ATP-binding dynein motor region D5 (2958 - 3183)

Dynein_heavy

Dynein_heavy: Dynein heavy chain and region D6 of dynein motor (3319 - 4021)

  • 0
  • 700
  • 1400
  • 2100
  • 2800
  • 3500
  • 4024 a.a.
Protein Preferred Names Protein Names

dynein axonemal heavy chain 7

  • axonemal beta dynein heavy chain 7

Related Diseases

Diseases Alias
Basal Ganglia Disease

  • Basal Ganglia Diseases

  • Basal Ganglia Disorders

  • Abnormality Of The Basal Ganglia
Situs Inversus

  • Situs Inversus Viscerum

  • Laterality Sequence

  • Complete Transposition

  • Siv
Primary Ciliary Dyskinesia

  • Immotile Cilia Syndrome

  • Kartagener Syndrome

  • Dextrocardia Bronchiectasis And Sinusitis

  • Pcd

  • Ciliary Motility Disorders

  • Ciliary Motility Disorder

  • Immotile Ciliary Syndrome

  • Ciliary Dyskinesia Primary

  • Ics

  • Polynesian Bronchiectasis

  • Dextrocardia-Bronchiectasis-Sinusitis Syndrome

  • Immotile Cilia Syndrome, Kartagener Type

  • Primary Ciliary Dyskinesia And Situs Inversus

  • Primary Ciliary Dyskinesia, Kartagener Type

  • Siewert Syndrome

  • Dyskinesia, Ciliary, Primary
Ciliary Dyskinesia, Primary, 36, X-Linked

  • CILD36

  • Ciliary Dyskinesia, Primary, 36, With Or Without Situs Inversus

  • Primary Ciliary Dyskinesia 36

  • X-Linked Primary Ciliary Dyskinesia 36
Ciliary Dyskinesia, Primary, 28

  • Primary Ciliary Dyskinesia 28

  • CILD28

  • Primary Ciliary Dyskinesia 28 With Or Without Situs Inversus

  • Ciliary Dyskinesia, Primary, 28, With Or Without Situs Inversus

  • Ciliary Dyskinesia, Primary, 28, Without Situs Inversus

  • Dyskinesia, Ciliary, Primary, 28
Kartagener Syndrome

  • Kartagener'S Syndrome
Visceral Heterotaxy

  • Situs Ambiguus

  • Heterotaxia

  • Heterotaxy Syndrome

  • Heterotaxy

  • Lateralization Defect

  • Situs Ambiguous

  • Left Isomerism

  • Htx

  • Ivemark Syndrome

  • Right Isomerism

  • Situs Ambiguus Viscerum

  • Incomplete Situs Inversus

  • Partial Situs Inversus

  • Heterotaxy, Visceral

  • Asplenia Syndrome

  • Bilateral Left-Sidedness

  • Polysplenia Syndrome

  • Moller Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03852 DNAH7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DNAH7 VGNC VGNC:49725
Felis catus DNAH7 VGNC VGNC:107525
Bos taurus DNAH7 VGNC VGNC:50052
Rattus norvegicus DNAH7 RGD RGD:621798
Macaca mulatta DNAH7 VGNC VGNC:71859
Others DNAH7 NCBI