GRIP2 - glutamate receptor interacting protein 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80852

About GRIP2

This gene has 7 transcripts (splice variants), 282 orthologues and 6 paralogues. Broad expression in heart (RPKM 7.1), spleen (RPKM 5.7) and 21 other tissues.

Summary

Predicted to enable protein C-terminus binding activity. Predicted to be involved in several processes, including neurotransmitter receptor transport, endosome to postsynaptic membrane; positive regulation of AMPA glutamate receptor clustering; and positive regulation of excitatory postsynaptic potential. Predicted to act upstream of or within Notch signaling pathway; artery smooth muscle contraction; and positive regulation of blood pressure. Predicted to be located in cytoplasm; dendritic shaft; and neuron spine. Predicted to be active in glutamatergic synapse and postsynaptic density. [provided by Alliance of Genome Resources, Apr 2022]

GRIP2 Products (1)

mRNA Protein Name
NM_001080423.4 NP_001073892.3 glutamate receptor-interacting protein 2
Protein Preferred Names Protein Names

glutamate receptor-interacting protein 2

Related Diseases

Diseases Alias
Fraser Syndrome 1

  • Fraser Syndrome

  • Cryptophthalmos With Other Malformations

  • Cryptophthalmos Syndrome

  • FRASRS1

  • Cryptophthalmos-Syndactyly Syndrome

  • Fraser-Francois Syndrome

  • Cyclopism

  • Meyer-Schwickerath'S Syndrome

  • Ulrich-Feichtiger Syndrome

  • Cryptophthalmos Syndactyly Syndrome

  • Fraser'S Syndrome

  • Meyer-Schwickerath Syndrome

  • Ullrich-Feichtiger Syndrome
Parkinson Disease 6, Autosomal Recessive Early-Onset

  • Autosomal Recessive Early-Onset Parkinson Disease 6

  • Parkinson Disease 6

  • PARK6

  • Parkinson Disease 6, Early Onset

  • Parkinson'S Disease 6

  • Parkinson Disease 6, Early-Onset

  • Autosomal Recessive Early-Onset Parkinson'S Disease 6

  • Early-Onset Parkinson Disease 6

  • Autosomal Recessive Early-Onset Parkinson Disease Type 6

  • Parkinson Disease 6 Early-Onset

  • Parkinson Disease 6 Late-Onset Susceptibility To

  • Parkinson Disease Autosomal Recessive Early-Onset Digenic Pink1/Dj1

  • Parkinsonism Young Adult Onset

  • Parkinson Disease, Autosomal Recessive Early-Onset, Digenic, Pink1/Dj1

  • Parkinson Disease, Type 6, Autosomal Recessive, Early-Onset
Hermansky-Pudlak Syndrome 1

  • Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

  • HPS1

  • Delta Storage Pool Disease

  • Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial

  • Hermansky-Pudlak Syndrome, Type 1

  • Platelet Storage Pool Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05810 GRIP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta GRIP2 VGNC VGNC:73221
Bos taurus GRIP2 VGNC VGNC:29652
Felis catus GRIP2 VGNC VGNC:62715
Canis familiaris GRIP2 VGNC VGNC:41499
Rattus norvegicus GRIP2 RGD RGD:621668
Mus musculus GRIP2 MGD MGI:2681173
Others GRIP2 NCBI