USP9Y - ubiquitin specific peptidase 9 Y-linked Gene

Also Known as DFFRY; SPGFY2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8287

About USP9Y

Cytogenetic location: Yq11.221 Genomic coordinates (GRCh38): Y:12,701,231-12,860,839 (from NCBI)

Summary

This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. [provided by RefSeq, Mar 2009]

USP9Y Products (1)

mRNA Protein Name
NM_004654.4 NP_004645.2 probable ubiquitin carboxyl-terminal hydrolase FAF-Y

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables cysteine-type deubiquitinase activity IDA
IDA: Inferred from direct assay
12895410 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

USP9Y Protein Structure

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (1559 - 1955)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 2000
  • 2400
  • 2555 a.a.
Protein Preferred Names Protein Names

probable ubiquitin carboxyl-terminal hydrolase FAF-Y

  • azoospermia factor A

Related Diseases

Diseases Alias
Spermatogenic Failure, Y-Linked, 2

  • SPGFY2

  • Spermatogenic Failure, Nonobstructive, Y-Linked

  • Y-Linked Spermatogenic Failure 2

  • Azoospermia, Nonobstructive, Y-Linked

  • Oligozoospermia, Nonobstructive, Y-Linked

  • Oligospermia, Nonobstructive, Y-Linked

  • Spermatogenic Arrest, Y-Linked

  • Nonobstructive Y-Linked Spermatogenic Failure

  • Spermatogenic Failure Y-Linked 2

  • Azoospermia Non-Obstructive Y-Linked

  • Non-Obstructive Azoospermia And Infertility

  • Oligospermia Non-Obstructive Y-Linked

  • Oligozoospermia Non-Obstructive Y-Linked

  • Spermatogenic Arrest Y-Linked

  • Spermatogenic Failure Nonobstructive Y-Linked
Partial Deletion Of Y

  • Partial Chromosome Y Deletion

  • Partial Deletion Of Y Chromosome Short Arm

  • Partial Deletion Of Chromosome Y

  • Partial Deletion Of The Long Arm Of The Y Chromosome

  • Y-Chromosome Microdeletions

  • Male Sterility Due To Chromosome Y Deletion

  • Y Chromosome Deletions
Male Infertility

  • Infertility, Male

  • Infertility Male

  • Male Sterility

  • Absolute Infertility
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Infertility
Phelan-Mcdermid Syndrome

  • Chromosome 22q13.3 Deletion Syndrome

  • 22q13.3 Deletion Syndrome

  • Telomeric 22q13 Monosomy Syndrome

  • PHMDS

  • Deletion 22q13 Syndrome

  • 22q13.3 Deletion

  • Deletion 22q13.3 Syndrome

  • Monosomy 22q13

  • Monosomy 22q13.3

  • 22q13 Deletion Syndrome

  • Monosomy 22q13 Syndrome

  • 22q13 Deletion

  • Chromosome Deletion
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15571 USP9Y Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20128 Usp9y Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26632 Usp9y Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus USP9Y MGD MGI:1313274
Rattus norvegicus USP9Y RGD RGD:9087771