Isotope-Labeled Compounds

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Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.

MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds (12438):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-14281S1

Trilostane-15N,d3		98%
Trilostane-¹⁵N,d₃ (Win 24540-¹⁵N,d₃) is the deuterium labeled Trilostane (HY-14281). Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane is a synthetic nonhormonal steroid. Trilostane can be used for the research of breast cancer and prostate cancer.

HY-14281S2

Trilostane-d3-1	2026644-48-2	98%
Trilostane-d₃-1 (Win 24540-d₃-1) is deuterium-labeled Trilostane (HY-14281).

HY-142828S

(Rac)-galaxolidone-d6		98%
(Rac)-galaxolidone-d₆ is the deuterium labeled (Rac)-galaxolidone.

HY-142842S

Carboxy primaquine-d4	2469039-32-3	98%
Carboxy primaquine-d₄ is the deuterium labeled Carboxy primaquine.

HY-142856S

Methapyrilene-d6 (hydrochloride)	2985926-49-4	98%
Methapyrilene-d₆ (hydrochloride) is the deuterium labeled Methapyrilene hydrochloride.

HY-142858S

3-Hydroxychrysene-d11	2468771-62-0	98%
3-Hydroxychrysene-d₁₁ is the deuterium labeled 3-Hydroxychrysene.

HY-142876S

Benz[a]anthracen-3-ol-d11		98%
Benz[a]anthracen-3-ol-d₁₁ is the deuterium labeled Benz[a]anthracen-3-ol.

HY-142887S

Mono(2-hydroxyisobutyl)phthalate-d4	2119597-90-7	98%
Mono(2-hydroxyisobutyl)phthalate-d₄ is the deuterium labeled Mono(2-hydroxyisobutyl)phthalate.

HY-14291S1

Vildagliptin-d7	1133208-42-0	98%
Vildagliptin-d₇ is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.

HY-14291S2

Vildagliptin-13C5,15N	1044741-01-6	98%
Vildagliptin-¹³C₅,¹⁵N (LAF237-¹³C₅,¹⁵N; NVP-LAF 237-¹³C₅,¹⁵N) is a ¹³C- and ¹⁵N-labeled Vildagliptin (HY-14291). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.

HY-14300AS

Vilanterol-d4 trifenatate	2021249-10-3	98%
Vilanterol-d₄ (trifenatate) is deuterium labeled Vilanterol (trifenatate).Vilanterol (GW642444) acetate is a long-acting β₂ adrenergic receptor agonist. Vilanterol acetate has pEC₅₀ values for β₂-AR, β₁-AR, and β₃-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol acetate selectively activates airway β₂ adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol acetate can be used in asthma research.

HY-143017S

4-Hydroxy Atorvastatin-d5 disodium		98%
4-Hydroxy Atorvastatin-d₅ (disodium) is the deuterium labeled 4-Hydroxy Atorvastatin disodium salt.

HY-143021S

1,3-Dioleoylglycerol-d5	1246523-70-5	98%
1,3-Dioleoylglycerol-d₅ is deuterium labeled 1,3-Dioleoylglycerol.

HY-14302S1

Salmeterol-d5	1093433-84-1	98%
Salmeterol-d5 is a deuterated labeled Salmeterol. Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC₅₀s of 9.6, 6.1, and 5.9, respectively.

HY-143030S

1,3-Dilinoleoyl-2-chloropropanediol-d5		98%
1,3-Dilinoleoyl-2-chloropropanediol-d₅ is the deuterium labeled 1,3-Dilinoleoyl-2-chloropropanediol (HY-W741803). 1,3-Dilinoleoyl-2-chloropropanediol is an ester product.

HY-143202S

DPhPC-d87
DPhPC-d₈7 is the deuterium labeled DPhPC (HY-143202). DPhPC is a phospholipid compound characterized by high mechanical and chemical stability, broad temperature phase stability, and high electrical resistance. DPhPC readily forms unilamellar vesicles and solid-supported bilayers. DPhPC is commonly used as a component of nanoliposomal drug carriers or as a model membrane material for studies on membrane proteins/ion channels.

HY-143355S

Albendazole-2-Aminosulfone-d3 hydrochloride	1435902-07-0	98%
Albendazole-2-Aminosulfone-d₃ (hydrochloride) is the deuterium labeled Albendazole-2-Aminosulfone (hydrochloride).

HY-143359S

COTI-219-d8		98%
COTI-219-d₈ is the deuterium labeled COTI-219.

HY-143504S

Mono(3-hydroxybutyl)phthalate-d4	2119601-77-1	98%
Mono(3-hydroxybutyl)phthalate-d₄ is the deuterium labeled Mono(3-hydroxybutyl)phthalate.

HY-143519S

Isopropyl phenyl-d7	2469037-60-1	98%
Isopropyl phenyl-d₇ is the deuterium labeled Isopropyl phenyl.

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