2. Academic Validation
  3. Synthesis and antitumoral activities of marine ent-chromazonarol and related compounds

Synthesis and antitumoral activities of marine ent-chromazonarol and related compounds

  • Bioorg Med Chem Lett. 1999 Aug 16;9(16):2325-8. doi: 10.1016/s0960-894x(99)00382-0.
A F Barrero 1,  E J Alvarez-Manzaneda,  M M Herrador,  R Chahboun,  P Galera
Affiliations

Affiliation

  • 1 Instituto de Biotecnologia, Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada, Spain. [email protected]
PMID: 10476862 DOI: 10.1016/s0960-894x(99)00382-0
Abstract

Efficient syntheses of ent-isozonarol (6a), ent-isozonarone (7a) and ent-chromazonarol (8) from (-)-sclareol (12) are described. 6a and 7a show a significative antitumoral activity.

Figures