2. Academic Validation
  3. Acyclic structural variants of growth hormone secretagogue L-692,429

Acyclic structural variants of growth hormone secretagogue L-692,429

  • Bioorg Med Chem Lett. 1999 Nov 15;9(22):3237-42. doi: 10.1016/s0960-894x(99)00568-5.
P Lin 1,  J M Pisano,  W R Schoen,  K Cheng,  W W Chan,  B S Butler,  R G Smith,  M H Fisher,  M J Wyvratt
Affiliations

Affiliation

  • 1 Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065, USA.
PMID: 10576695 DOI: 10.1016/s0960-894x(99)00568-5
Abstract

Systematic investigation of acyclic analogs of L-692,429, the prototype benzolactam growth hormone secretagogue, has helped to further define the structural requirements for the release of growth hormone from rat pituitary cells for this class of secretagogues.

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