2. Academic Validation
  3. 7-Methoxybenzofuran-4-carboxamides as PDE 4 inhibitors: a potential treatment for asthma

7-Methoxybenzofuran-4-carboxamides as PDE 4 inhibitors: a potential treatment for asthma

  • Bioorg Med Chem Lett. 2000 Sep 18;10(18):2137-40. doi: 10.1016/s0960-894x(00)00426-1.
G Buckley 1,  N Cooper,  H J Dyke,  F Galleway,  L Gowers,  J C Gregory,  D R Hannah,  A F Haughan,  P G Hellewell,  H J Kendall,  C Lowe,  R Maxey,  J G Montana,  R Naylor,  C L Picken,  K A Runcie,  V Sabin,  B R Tuladhar,  J B Warneck
Affiliations

Affiliation

  • 1 Celltech-Chiroscience Ltd, Abington, Cambridge, UK.
PMID: 10999488 DOI: 10.1016/s0960-894x(00)00426-1
Abstract

The synthesis and pharmacological profile of a novel series of 7-methoxybenzofuran-4-carboxamides is described. Some of these compounds were found to be potent inhibitors of phosphodiesterase type 4 (PDE4).

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