2. Academic Validation
  3. Synthesis and antiproliferative activity of benzocyclobutacarbazol derivatives. A new class of potential antitumor agents

Synthesis and antiproliferative activity of benzocyclobutacarbazol derivatives. A new class of potential antitumor agents

  • Bioorg Med Chem Lett. 2000 Dec 4;10(23):2589-91. doi: 10.1016/s0960-894x(00)00532-1.
S Graf-Christophe 1,  C Kuehm-Caubère,  P Renard,  B Pfeiffer,  A Pierré,  S Léonce,  P Caubère
Affiliations

Affiliation

  • 1 Institut de Chimie Organique et Analytique, associé au CNRS, Université d'Orléans, France.
PMID: 11128630 DOI: 10.1016/s0960-894x(00)00532-1
Abstract

Several benzocyclobutacarbazol derivatives were synthesized and evaluated for their potential cytotoxic properties. A number of these compounds exhibited significant antiproliferative activity with concomitant interaction with the cell cycle and represent a new class of potential Anticancer agents.

Figures