1. Academic Validation
  2. Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei

Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei

  • Phytochemistry. 2001 Oct;58(4):627-9. doi: 10.1016/s0031-9422(01)00248-5.
X C Li 1 D C Dunbar H N ElSohly L A Walker A M Clark
Affiliations

Affiliation

  • 1 National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, USA.
Abstract

The indolopyridoquinazoline alkaloid, 3-hydoxyrutaecarpine, was isolated from Leptothyrsa sprucei, along with 8-methoxypsoralen, 5-methoxypsoralen, imperatorin, isoimperatorin, kaempferol 3-O-alpha-L-rhamnopyranoside, clematine and cnidioside B. The usefulness of the gradient 1H-15N HMBC NMR spectroscopy in the structure elucidation of 3-hydroxyrutaecarpine is noted.

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