1. Academic Validation
  2. Synthesis and biological activity of the new 5-fluorocytosine derivatives, 5'-deoxy-N-alkyloxycarbonyl-5-fluorocytosine-5'-carboxylic acid

Synthesis and biological activity of the new 5-fluorocytosine derivatives, 5'-deoxy-N-alkyloxycarbonyl-5-fluorocytosine-5'-carboxylic acid

  • Bioorg Med Chem Lett. 2002 Feb 11;12(3):483-6. doi: 10.1016/s0960-894x(01)00782-x.
Kwan-Hee Kim 1 Ji-Young Kim Keyong-Ho Lee Moon-Jong Noh Youn-Chul Kim Ho-Jin Park
Affiliations

Affiliation

  • 1 Biomedical Research Institute, Kolon Central Research Park, 207-2Mabuk-Ri, Guseong-Eup, Yongin-City, Kyunggi-Do 449-797, Republic of Korea. [email protected]
Abstract

A series of 5-fluorocytosine derivatives, 5'-deoxy-N-alkyloxycarbonyl-5-fluorocytosine-5'-carboxylic acid 6, were synthesized and evaluated for their antitumor activity.

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