2. Academic Validation
  3. 7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: a potential treatment for asthma

7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: a potential treatment for asthma

  • Bioorg Med Chem Lett. 2002 Feb 11;12(3):509-12. doi: 10.1016/s0960-894x(01)00786-7.
George M Buckley 1,  Nicola Cooper,  Richard J Davenport,  Hazel J Dyke,  Fiona P Galleway,  Lewis Gowers,  Alan F Haughan,  Hannah J Kendall,  Christopher Lowe,  John G Montana,  Janet Oxford,  Joanna C Peake,  C Louise Picken,  Marianna D Richard,  Verity Sabin,  Andrew Sharpe,  Julie B H Warneck
Affiliations

Affiliation

  • 1 Celltech R & D, Granta Park, Great Abington, Cambridge CB1 6GS, UK.
PMID: 11814830 DOI: 10.1016/s0960-894x(01)00786-7
Abstract

The synthesis and pharmacological profile of a novel series of 7-methoxy-furo[2,3-c]pyridine-4-carboxamides is described. Some of these compounds were found to be potent inhibitors of phosphodiesterase type 4 (PDE4).

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