2. Academic Validation
  3. A case of sectorial benign flecked retina

A case of sectorial benign flecked retina

  • Jpn J Ophthalmol. 2004 Jan-Feb;48(1):72-4. doi: 10.1007/s10384-003-0002-6.
Takako Tsuchiya 1,  Masaru Kato,  Natsuyo Tomita,  Kenro Koide,  Norimasa Hata,  Miho Sato,  Yoshihiro Hotta,  Makoto Ueno,  Makoto Nakamura,  Yozo Miyake
Affiliations

Affiliation

  • 1 Department of Ophthalmology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
PMID: 14767656 DOI: 10.1007/s10384-003-0002-6
Abstract

Purpose: A case of sectorial benign flecked retina not associated with an RDH5 gene mutation is reported.

Methods: A 51-year-old woman showed multiple yellow-white flecks in both eyes similar to those of benign flecked retina but in only the upper half of the retina. We carried out clinical, electrophysiological, and molecular genetic examinations of the patient.

Results: Visual acuity was 20/20 OD and 20/20 OS. Fluorescein angiography showed diffuse irregular hypofluorescence that did not correspond to the flecked lesions. A Goldmann-Weeker adaptometer test revealed that the visual threshold of the upper retina was approximately 0.6 to 0.8 log units higher than that of the lower retina. No mutations of the RDH5 gene were detected in exons 2-5 or in the flanking intron sequences.

Conclusions: To our knowledge, this is the first report of sectorial benign flecked retina, and the flecks may not be caused by an RDH5 gene mutation.

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