2. Academic Validation
  3. Design, synthesis and structure-activity relationship of novel RXR-selective modulators

Design, synthesis and structure-activity relationship of novel RXR-selective modulators

  • Bioorg Med Chem Lett. 2004 Mar 22;14(6):1593-8. doi: 10.1016/j.bmcl.2003.12.089.
Pierre-Yves Michellys 1,  Jennifer D'Arrigo,  Timothy A Grese,  Donald S Karanewsky,  Mark D Leibowitz,  Dale A Mais,  Christopher M Mapes,  Anne Reifel-Miller,  Deepa Rungta,  Marcus F Boehm
Affiliations

Affiliation

  • 1 Department of Medicinal Chemistry, Ligand Pharmaceuticals Incorporated, 10275 Science Center Drive, San Diego, CA 92121, USA. [email protected]
PMID: 15006411 DOI: 10.1016/j.bmcl.2003.12.089
Abstract

The synthesis and in vitro characterization of novel RXR-selective ligands possessing various substituted 1-benzofuran or 1-benzothiophene moieties are described.

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