2. Academic Validation
  3. New benzo[5,6]pyrrolizino[1,2-b]quinolines as cytotoxic agents

New benzo[5,6]pyrrolizino[1,2-b]quinolines as cytotoxic agents

  • Bioorg Med Chem Lett. 2004 May 3;14(9):2363-5. doi: 10.1016/j.bmcl.2004.01.097.
Aurore Perzyna 1,  Frédérique Klupsch,  Raymond Houssin,  Nicole Pommery,  Amélie Lemoine,  Jean-Pierre Hénichart
Affiliations

Affiliation

  • 1 Institut de Chimie Pharmaceutique Albert Lespagnol, EA 2692, Université de Lille, 2, rue du Professeur Laguesse, BP 83, 59006 Lille, France.
PMID: 15081041 DOI: 10.1016/j.bmcl.2004.01.097
Abstract

An assessment of structure-activity relationships associated with the new benzo[5,6]pyrrolizino[1,2-b]quinoline system displaying potent in vitro cytotoxic activity against the MCF7 cell line is described.

Figures