2. Academic Validation
  3. Metabolic and molecular basis of peroxisomal disorders: a review

Metabolic and molecular basis of peroxisomal disorders: a review

  • Am J Med Genet A. 2004 May 1;126A(4):355-75. doi: 10.1002/ajmg.a.20661.
Ronald J A Wanders 1
Affiliations

Affiliation

  • 1 University of Amsterdam, Academic Medical Centre, Department of Clinical Chemistry, Emma Children's Hospital, Laboratory of Genetic Metabolic Diseases, Amsterdam, The Netherlands. [email protected]
PMID: 15098234 DOI: 10.1002/ajmg.a.20661
Abstract

The group of peroxisomal disorders now includes 17 different disorders with Zellweger syndrome as prototype. Thanks to the explosion of new information about the functions and biogenesis of peroxisomes, the metabolic and molecular basis of most of the peroxisomal disorders has been resolved. A review of peroxisomal disorders is provided in this paper.

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