2. Academic Validation
  3. Identification and optimization of novel partial agonists of neuromedin B receptor using parallel synthesis

Identification and optimization of novel partial agonists of neuromedin B receptor using parallel synthesis

  • Bioorg Med Chem Lett. 2004 Jun 21;14(12):3037-42. doi: 10.1016/j.bmcl.2004.04.045.
Stephen J Shuttleworth 1,  Mike E Lizarzaburu,  Anne Chai,  Peter Coward
Affiliations

Affiliation

  • 1 Department of Chemistry, Tularik Inc., 1120 Veterans Boulevard, South San Francisco, CA 94080, USA.
PMID: 15149640 DOI: 10.1016/j.bmcl.2004.04.045
Abstract

The design and parallel synthesis of potent, small molecule partial agonists of Neuromedin B receptor based on the 3-amino-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid amide core is described.

Figures