2. Academic Validation
  3. Triterpenoid saponins from leaves of Hedera pastuchowii

Triterpenoid saponins from leaves of Hedera pastuchowii

  • Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1411-5. doi: 10.1248/cpb.52.1411.
Vakhtang Mshvildadze 1,  Riad Elias,  Robert Faure,  David Rondeau,  Laurent Debrauwer,  Genri Dekanosidze,  Ether Kemertelidze,  Guy Balansard
Affiliations

Affiliation

  • 1 Institute of Pharmacochemistry, Academy of Sciences of Georgia, Tbilisi, Georgia.
PMID: 15577235 DOI: 10.1248/cpb.52.1411
Abstract

Five new triterpenoid saponins, pastuchoside A (1), B (3), C (5), D (7) and E (9), were isolated from the leaves of Hedera pastuchowii. They have oleanolic acid or hederagenin as aglycone. The structures were established by NMR spectroscopy including gs (gradient selected)-COSY, gs-HSQC, gs-HSQC-TOCSY and gs-HMBC experiments, and mass spectrometry (ESI-HR-MS). Heptaoside saponins, compounds 1 and 3, are described for the first time in the genus Hedera.

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