1. Academic Validation
  2. Bioactive constituents from roots of Bursera tonkinensis

Bioactive constituents from roots of Bursera tonkinensis

  • Phytochemistry. 2005 Dec;66(23):2745-51. doi: 10.1016/j.phytochem.2005.09.025.
Aranya Jutiviboonsuk 1 Hongjie Zhang Ghee Teng Tan Cuiying Ma Nguyen Van Hung Nguyen Manh Cuong Nuntavan Bunyapraphatsara D Doel Soejarto Harry H S Fong
Affiliations

Affiliation

  • 1 Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, 447 Si Ayutthaya Road, Ratchathewi District, Bangkok 10400, Thailand.
Abstract

Bioassay directed-fractionation led to isolation of 12 compounds from the roots of Bursera tonkinensis Guillaum (Burseraceae), including burselignan, bursephenylpropane, and burseneolignan. Of the 12 compounds, only 4'-demethyldesoxypodophyllotoxin exhibited significant cytotoxic activities against KB, Col2 and LNCaP cell lines.

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