2. Academic Validation
  3. Hyosgerin, a new optically active coumarinolignan, from the seeds of Hyoscyamus niger

Hyosgerin, a new optically active coumarinolignan, from the seeds of Hyoscyamus niger

  • Chem Pharm Bull (Tokyo). 2006 Apr;54(4):538-41. doi: 10.1248/cpb.54.538.
Begum Sajeli 1,  Mahendra Sahai,  Roderich Suessmuth,  Teigo Asai,  Noriyuki Hara,  Yoshinori Fujimoto
Affiliations

Affiliation

  • 1 Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. [email protected]
PMID: 16595960 DOI: 10.1248/cpb.54.538
Abstract

Hyosgerin, a new optically active coumarinolignan, has been isolated and characterized along with three other coumarinolignans, venkatasin, cleomiscosin A and cleomiscosin B, from the seeds of Hyoscyamus niger L. The structure was determined on the basis of spectroscopic analysis and chemical conversion. The optical properties and absolute stereochemistry of these coumarinolignans have also been studied and discussed.

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