1. Academic Validation
  2. Five new iridoids from Patrinia rupestris

Five new iridoids from Patrinia rupestris

  • Chem Biodivers. 2006 Jul;3(7):762-70. doi: 10.1002/cbdv.200690078.
Xiu-Ping Yang 1 Er-Wei Li Qi Zhang Cheng-Shan Yuan Zhong-Jian Jia
Affiliations

Affiliation

  • 1 State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, 730000, PR China.
Abstract

Five new Iridoids, namely rupesin A-E (1-5, resp.), together with six known Iridoids, 6-11, were isolated from the roots of Patrinia rupestris. Their structures were elucidated by spectroscopic methods including IR, UV, MS, and 1D- and 2D-NMR experiments, and comparison with data of known analogues. Compounds 4 and 11, compounds 1, 2, 5, 6, 8, 9, and 10, and compounds 3, 4, and 8 showed significant Antibacterial activities against Bacillus subtilis, Escherichia coli, and Staphylococcus aureus, respectively.

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