2. Academic Validation
  3. Fluorogenic and chromogenic rhodamine spirolactam based probe for nitric oxide by spiro ring opening reaction

Fluorogenic and chromogenic rhodamine spirolactam based probe for nitric oxide by spiro ring opening reaction

  • Org Lett. 2008 Jun 19;10(12):2357-60. doi: 10.1021/ol800206x.
Hong Zheng 1,  Gui-Qin Shang,  Shi-Yao Yang,  Xia Gao,  Jin-Gou Xu
Affiliations

Affiliation

  • 1 Key Laboratory of Analytical Sciences, Ministry of Education, and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China. [email protected]
PMID: 18484726 DOI: 10.1021/ol800206x
Abstract

A new fluorogenic and chromogenic probe rhodamine B spirolactam (1) was developed that in aqueous solutions exhibited a highly selective and sensitive "turn-on" type spectral response toward NO detection following a NO-induced spiro-ring opening reaction in 1.

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