2. Academic Validation
  3. Propindilactones E-J, Schiartane Nortriterpenoids from Schisandra propinqua var. propinqua

Propindilactones E-J, Schiartane Nortriterpenoids from Schisandra propinqua var. propinqua

  • J Nat Prod. 2008 Jul;71(7):1228-32. doi: 10.1021/np8001699.
Chun Lei 1,  Sheng-Xiong Huang,  Ji-Jun Chen,  Li-Bin Yang,  Wei-Lie Xiao,  Yin Chang,  Yang Lu,  Hao Huang,  Jian-Xin Pu,  Han-Dong Sun
Affiliations

Affiliation

  • 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
PMID: 18578539 DOI: 10.1021/np8001699
Abstract

Six new nortriterpenoids, propindilatones E-J (1-6), and two known (7, 8) schiartane-type nortriterpenoids were isolated from the stems of Schisandra propinqua var. propinqua. Their structures were elucidated by extensive spectroscopic analyses, and the structure of compound 4 was confirmed through single-crystal X-ray diffraction. The absolute configuration of compounds 1-3 was established using CD methods. Compounds 4-6 were noncytotoxic against K562, A549, and HT-29 human Cancer cells.

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