2. Academic Validation
  3. Labdane diterpenes from the rhizomes of Hedychium coronarium

Labdane diterpenes from the rhizomes of Hedychium coronarium

  • Nat Prod Res. 2008;22(14):1249-56. doi: 10.1080/14786410701726434.
Nitirat Chimnoi 1,  Somchai Pisutjaroenpong,  Lukana Ngiwsara,  Decha Dechtrirut,  Daranee Chokchaichamnankit,  Nisachon Khunnawutmanotham,  Chulabhorn Mahidol,  Supanna Techasakul
Affiliations

Affiliation

  • 1 Chulabhorn Research Institute, Bangkok 10210, Thailand.
PMID: 18932088 DOI: 10.1080/14786410701726434
Abstract

A new labdane diterpenoid, (E)-labda-8(17),12-dien-15,16-olide (1) together with eight known compounds, coronarin D (2), coronarin D methyl ether (3), coronarin D ethyl ether (4), isocoronarin D (5), coronarin B (6), labda-8(17),11,13-trien-15,16-olide (7), (E)-labda-8(17),12-diene-15,16-dial (8) and 16-hydroxylabda-8(17),11,13-trien-15,16-olide (9), are isolated from the rhizomes of Hedychium coronarium. Compounds 2-4, 5 and 9 are isolated as mixtures of C-15, C-14 and C-16 epimers, respectively. Their structures are determined on the basis of their spectroscopic data. The epimeric mixtures of 2 and 3 have not been reported before. Some of them were evaluated for their cytotoxicity.

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