2. Academic Validation
  3. Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from Scleria striatinux with antiplasmodial activity

Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from Scleria striatinux with antiplasmodial activity

  • J Nat Prod. 2009 Feb 27;72(2):280-3. doi: 10.1021/np800338p.
Simon M N Efange 1,  Reto Brun,  Sergio Wittlin,  Joseph D Connolly,  Thomas R Hoye,  Thomas McAkam,  Felix L Makolo,  James A Mbah,  Dorian P Nelson,  Kennedy D Nyongbela,  Clare K Wirmum
Affiliations

Affiliation

  • 1 Department of Chemistry, University of Buea, PO Box 63, Buea, Southwest Province, Cameroon. [email protected]
PMID: 19199815 DOI: 10.1021/np800338p
Abstract

Okundoperoxide (1) was isolated by bioassay-guided fractionation of extracts from Scleria striatinux (syn. S. striatonux). The compound contains a cyclic endoperoxide structural moiety and possesses moderate antimalarial activity.

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