2. Academic Validation
  3. Utility of 16S ribosomal DNA sequencing in the diagnosis of Staphylococcus lugdunensis native valve infective endocarditis: case report and literature review

Utility of 16S ribosomal DNA sequencing in the diagnosis of Staphylococcus lugdunensis native valve infective endocarditis: case report and literature review

  • Int J Infect Dis. 2009 Nov;13(6):e511-3. doi: 10.1016/j.ijid.2009.02.019.
Surinder Pada 1,  David C Lye,  Yee Sin Leo,  Timothy Barkham
Affiliations

Affiliation

  • 1 Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433. [email protected]
PMID: 19447659 DOI: 10.1016/j.ijid.2009.02.019
Abstract

We report a case of possible infective endocarditis without fever presenting with an acutely ischemic limb with prior antimicrobial therapy preventing identification by culture of a microorganism. 16S ribosomal DNA sequencing led to the identification of Staphylococcus lugdunensis from an embolus removed at surgery and subsequent successful Antibiotic treatment. We review the utility of 16S ribosomal DNA sequencing in diagnosing infective endocarditis and other infectious conditions.

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