1. Academic Validation
  2. Three new antioxidant C-glucosylanthrones from Aloe nobilis

Three new antioxidant C-glucosylanthrones from Aloe nobilis

  • J Asian Nat Prod Res. 2010 Jun;12(6):443-7. doi: 10.1080/10286020.2010.490211.
Liang Lv 1 Xiao-Yan Tian Wei-Shuo Fang
Affiliations

Affiliation

  • 1 Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Peking Union Medical College), Ministry of Education, Beijing, China.
Abstract

Three new C-glucosylanthrones, 3'-O-acetyl-5-hydroxylaloin A (2), 2',6'-O-diacetyl-5-hydroxylaloin A (4), and 4',6'-O-diacetyl-5-hydroxylaloin A (5), along with three known compounds, 5-hydroxyaloin A (1), 6'-acetyl-5-hydroxylaloin A (3), and 4-methoxy-6-(2',4'-dihydroxy-6'-methylphenyl)-pyran-2-one (6), were isolated from the leaves of Aloe nobilis, and their structures were elucidated on the basis of spectroscopic evidences. Compounds 1, 2, 4 and 5 showed antioxidant activity with inhibitory rates of 31.0, 34.0, 34.0, and 42.0%, respectively, at 10(-5) M.

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