2. Academic Validation
  3. [Studies on pharmacologically active principles from Indonesian crude drugs. III. Toxic components from Brucea javanica (L.) Merr]

[Studies on pharmacologically active principles from Indonesian crude drugs. III. Toxic components from Brucea javanica (L.) Merr]

  • Yakugaku Zasshi. 1990 Nov;110(11):834-8. doi: 10.1248/yakushi1947.110.11_834.
E Okuyama 1,  L H Gao,  M Yamazaki
Affiliations

Affiliation

  • 1 Faculty of Pharmaceutical Sciences, Chiba University, Japan.
PMID: 2082013 DOI: 10.1248/yakushi1947.110.11_834
Abstract

During our screening of pharmacologically active principles from Indonesian medicinal Plants by a hypothermic effect the methanol-extract of Brucea javanica (L.) Merr. has been found to exhibit a lethal toxicity to mice. The toxic components were isolated and identified with bruceoside A and B and yadanzioside F. Correction of 13C-nuclear magnetic resonance assignment was also mentioned.

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