2. Academic Validation
  3. Chemical constituents of the leaves of Glochidion obliquum and their bioactivity

Chemical constituents of the leaves of Glochidion obliquum and their bioactivity

  • Arch Pharm Res. 2011 Mar;34(3):383-9. doi: 10.1007/s12272-011-0305-y.
Tran Dinh Thang 1,  Ping-Chung Kuo,  Chun-Shu Yu,  Yuh-Chiang Shen,  Le Thi Mai Hoa,  Tran Van Thanh,  Yao-Haur Kuo,  Mei-Lin Yang,  Tian-Shung Wu
Affiliations

Affiliation

  • 1 Department of Chemistry, Vinh University, Vinh City, Nghean province, Vietnam.
PMID: 21547669 DOI: 10.1007/s12272-011-0305-y
Abstract

A new flavonoid glycoside, globlin A (1), and eleven known compounds were isolated from methanolic extracts of the leaves of Glochidion obliquum. The structure of this new compound was established with a combination of 2D NMR techniques (COSY, NOESY, HMQC and HMBC) and HR-ESI-MS analyses. Chemical structures of the other known compounds were identified by comparison of their spectroscopic and physical data with those reported in the literature. Some of the isolates were examined for their bioactivities. Among the tested compounds, rotundic acid (4) displayed significant cytotoxicity and anti-inflammatory activities.

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