1. Academic Validation
  2. Do you know this syndrome?

Do you know this syndrome?

  • An Bras Dermatol. 2011 May-Jun;86(3):605-7. doi: 10.1590/s0365-05962011000300036.
Isabela Guimarães Ribeiro Baeta 1 Ana Carolina Figueiredo Pereira Antônio Carlos Martins Guedes Luciana Baptista Pereira
Affiliations

Affiliation

  • 1 Dermatology Outpatient Department, Teaching Hospital of the Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil. [email protected]
Abstract

Keratosis linearis with ichthyosis congenita and sclerosing keratoderma (KLICK) syndrome is a rare autosomal recessive skin disorder characterized by the association of diffuse, transgressive palmoplantar keratoderma with sclerodactyly, linear hyperkeratotic plaques generally located in flexures, and congenital ichthyosis. The patient is physically and mentally healthy and has no history of any problems related to teeth, nails, hair or mucous membranes. Treatment is based on the use of topical keratolytics and oral retinoids.

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