2. Academic Validation
  3. Complete genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10

Complete genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10

  • J Bacteriol. 2011 Dec;193(24):7005. doi: 10.1128/JB.06284-11.
Shuting Lu 1,  Xiaobing Zhang,  Yafang Zhu,  Kwang Sik Kim,  Jian Yang,  Qi Jin
Affiliations

Affiliation

  • 1 State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy Medical Sciences & Peking Union Medical College, Beijing 100176, China.
PMID: 22123760 DOI: 10.1128/JB.06284-11
Abstract

Neonatal Bacterial meningitis continues to be an important cause of mortality and morbidity worldwide. Escherichia coli possessing the K1 capsular polysaccharide is the most common Gram-negative pathogen causing neonatal meningitis. Here we present the complete genome sequence of neonatal meningitis-associated E. coli strain CE10, a unique K1 strain with a functional type III secretion system. Functional analysis of the genome should enhance our knowledge of the pathogenesis of neonatal E. coli K1 meningitis.

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