1. Academic Validation
  2. Chlorantholides A-F, eudesmane-type sesquiterpene lactones from Chloranthus elatior

Chlorantholides A-F, eudesmane-type sesquiterpene lactones from Chloranthus elatior

  • Phytochemistry. 2012 May:77:312-7. doi: 10.1016/j.phytochem.2012.02.008.
Fei Wang 1 Dong-Sheng Zhou Guo-Zhu Wei Fu-Cai Ren Ji-Kai Liu
Affiliations

Affiliation

  • 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. [email protected]
Abstract

Six eudesmane-type sesquiterpene lactones, named chlorantholides A-F, were isolated from the ethanol extract of Chloranthus elatior (Chloranthaceae) together with 12 known compounds. Their structures were elucidated on the basis of extensive spectroscopic analysis, and their absolute configurations were studied by the CD exciton chirality method. The structure of a recently reported eudesmanolide from Chloranthus anhuiensis: 8β-hydroxy-1-oxoeudesma-3,7(11)-dien-12,8-olide, was also revised as 8β-hydroxy-2-oxoeudesma-3,7(11)-dien-12,8-olide (chlorantholide D).

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