Chloranthaceae Extract
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- Sarcandra glabra (Thunb.) Nakai Extract (10)
- Chloranthus erectus (Buchanan-Hamilton) Verdcourt Extract (8)
- Chloranthus serratus (Thunb.) Roem. et Schult. Extract (8)
- Chloranthus spicatus (Thunb.) Makino Extract (8)
- Chloranthus japonicus Sieb. Extract (4)
- Chloranthus fortunei (A. Gray) Solms-Laub Extract (2)
- Chloranthus henryi Hemsl. Extract (2)
- Chloranthus holostegius (Hand.-Mazz.) Pei et Shan Extract (2)
- Chloranthus anhuiensis K. F. Wu Extract (1)
- Chloranthus serratus var. taiwanensis K. F. Wu Extract (1)
- Hedyosmum brasiliense Mart. Extract (1)
- Sarcandra glabra subsp. brachystachys (Blume) Verdcourt Extract (1)
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Chloranthaceae Extract (51)
- 화학식: C40H44O13
- 분자량: 732.77
Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-α, and IL-1β expression.
- 화학식: C31H34O6
- 분자량: 502.60
Shizukaol A is an sesquiterpene dimer that can be isolated from Chloranthus japonicas.
- 화학식: C17H18O4
- 분자량: 286.32
Chlojaponilactone B is a lindenane-type sesquiterpenoid with anti-inflammatory properties. Chlojaponilactone B suppresses inflammatory responses by inhibiting TLR4 and subsequently decreasing reactive oxygen species (ROS) generation, downregulating the NF-κB, thus reducing the expression of the pro-inflammatory cytokines iNOS, NO, COX-2, IL-6 and TNF-α.
- 화학식: C15H16O3
- 분자량: 244.29
- 화학식: C39H42O14
- 분자량: 734.74
Chloramultilide B is a lindenane dimer that can be isolated from Chloranthus serratus. Chloramultilide B has inhibitory activities against Candida albicans and C.parapsilosis with a MIC value of 0.068 μM.
- 화학식: C33H36O9
- 분자량: 576.63
Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 μM.
- 화학식: C17H16O4
- 분자량: 284.31
(E/Z)-Flavokawain B (compound 4) is a chalcone and nitric oxide production inhibitor with an IC50 of 6.8 μM.(E/Z)-Flavokawain B can be found in the aerial parts of Sarcandra glabra.(E/Z)-Flavokawain B inhibits lipopolysaccharide-induced nitric oxide production.
- 화학식: C15H20O3
- 분자량: 248.32
Shizukolidol is an antimicrobial agent that can be isolated from polyfollicles of Magnolia vovidessi. Shizukolidol shows antibacterial activity against Chryseobacterium sp. Shizukolidol can be used for the research of bacterial infection.
- 화학식: C27H32O5
- 분자량: 436.54
Glabralide A is a natural chalcone.
- 화학식: C21H26O3
- 분자량: 326.43
Glabralide B is a natural phenolic compound.
- 화학식: C17H20O4
- 분자량: 288.34
Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research.
- 화학식: C15H18O3
- 분자량: 246.30
Chlorantholide C, an eudesmane-type sesquiterpene lactone, can be isolated from Chloranthus elatior.
- 화학식: C33H38O9
- 분자량: 578.65
- 화학식: C38H44O12
- 분자량: 692.75
Sarglaroids F (compound 6) is an anti-inflammatory agent isolated from the roots of Grass Coral. Sarglaroids F inhibits LPS/ATP-induced IL-1β release by affecting K+ efflux and reducing Caspase-1(P20) levels. Sarglaroids F is not cytotoxic to RAW264.7 cells.
- 화학식: C15H26O2
- 분자량: 238.37
Aromadendrane-4β,10α-diol is a sesquiterpene alcohol. Aromadendrane-4β,10α-diol significantly ameliorates the Aβ1-42 peptide-induced memory impairment. Aromadendrane-4β,10α-diol can be used for Alzheimer's disease (AD) research.
- 화학식: C32H36O8
- 분자량: 548.62
Cycloshizukaol A is a symmetrical cyclic lindenane dimer with C2 symmetry. Cycloshizukaol A can be isolated from the root of Chloranthus serratus.
- 화학식: C29H40O4
- 분자량: 452.63
Glabralide C is a meroterpenoid. Glabralide C can be isolated from Sarcandra glabra.
- 화학식: C15H18O4
- 분자량: 262.30
8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide (compound 3), a sesquiterpene, has anti-LIMK1 activity. 8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide has inhibitory property on cell motility.
- 화학식: C16H20O4
- 분자량: 276.33
8-epi-Chlorajapolide F (compound 1) a sesquiterpene that can be isolated from the aboveground part of the Chloranthus japonicus. 8-epi-Chlorajapolide has few cytotoxic to human cancer cell lines NCI-H460 and SMMC-7721 (IC50s>50 μg/mL).
