- Natural Products
- Plants
- Chloranthaceae Extract
- Chloranthus holostegius (Hand.-Mazz.) Pei et Shan
Chloranthus holostegius (Hand.-Mazz.) Pei et Shan
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Chloranthus holostegius (Hand.-Mazz.) Pei et Shan (2)
- Formula: C33H36O9
- Molecular Weight: 576.63
Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 μM.
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- Formula: C38H44O11
- Molecular Weight: 676.75
Chlorahololide D is a potent and selective Potassium Channel blocker with an IC50 value of 2.7 μM. Chlorahololide D is a nature product that could be isolated from the whole plant of Chloranthus holostegius.
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