2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Chlorahololide C

Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 μM.

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Chlorahololide C Chemical Structure

Chlorahololide C Chemical Structure

CAS No. : 1007859-25-7

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Based on 1 publication(s) in Google Scholar

Chlorahololide C Related Antibodies

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Description

Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 μM[1].

IC50 & Target

IC50: 3.6 μM (potassium channel)[1]
In Vitro

Chlorahololide C (0.1-100 μM) inhibits the delayed rectifier K+ current (IK) in rat dissociated hippocampal neurons, with an IC50 of 3.6 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chlorahololide C Related Antibodies
Molecular Weight

576.63

Formula

C33H36O9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC(/C(C)=C1C2=C([C@]([C@@]3([H])[C@]4([H])C3)([C@H](C/1=O)O)C)[C@]4(O)C[C@]([C@@]5([C@@](C([C@]6([H])[C@@]5([H])C6)=C)([H])[C@H]7OC(C)=O)C)([H])[C@@]28C7=C(C(O8)=O)C)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: ≥98.0%

COA (267 KB)

Handling Instructions (2659 KB)
References
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Chlorahololide C Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chlorahololide C1007859-25-7Potassium ChannelKcsAlindenanesesquiterpenoiddimerChloranthusholostegiuspotassiumchannelblockerInhibitorinhibitorinhibit

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