Chlorahololide C
Based on 1 Customer Validation
Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 μM.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 1007859-25-7
- Formula: C33H36O9
- Molecular Weight:576.63
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: 3.6 μM (potassium channel)[1]
In Vitro
Chlorahololide C (0.1-100 μM) inhibits the delayed rectifier K+ current (IK) in rat dissociated hippocampal neurons, with an IC50 of 3.6 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1007859-25-7
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Appearance Solid
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Molecular Weight 576.63
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Formula C33H36O9
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Color White to off-white
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SMILES
COC(/C(C)=C1C2=C([C@]([C@@]3([H])[C@]4([H])C3)([C@H](C/1=O)O)C)[C@]4(O)C[C@]([C@@]5([C@@](C([C@]6([H])[C@@]5([H])C6)=C)([H])[C@H]7OC(C)=O)C)([H])[C@@]28C7=C(C(O8)=O)C)=O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chlorahololide C Related Classifications
HY-N8404 Related Classifications
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