Chlorahololide D
Chlorahololide D is a potent and selective Potassium Channel blocker with an IC50 value of 2.7 μM. Chlorahololide D is a nature product that could be isolated from the whole plant of Chloranthus holostegius.
For research use only. We do not sell to patients.
- CAS No.: 943136-39-8
- Formula: C38H44O11
- Molecular Weight:676.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| WI-38 | IC50 |
0.16 μM
Compound: 20
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Cytotoxicity against human WI38 cells after 72 hrs by CCK8 assay
Cytotoxicity against human WI38 cells after 72 hrs by CCK8 assay
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[PMID: 27997206] |
Chemical Information
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CAS No. 943136-39-8
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Molecular Weight 676.75
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Formula C38H44O11
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SMILES
COC(/C(C)=C1[C@]2([H])[C@@]34[C@](CC5=C2[C@]([C@@]6([H])[C@]5([H])C6)([C@H](C/1=O)O)C)([H])[C@]7([C@@]8([H])[C@]([C@](O)([C@]7([H])CC3=C(C(O4)=O)COC(C)=O)COC(/C(C)=C/C)=O)([H])C8)C)=O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chlorahololide D Related Classifications
HY-N3573 Related Classifications
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