943136-39-8
Chemical Structure
Chlorahololide D
- CAS No.: 943136-39-8
- Formula:C38H44O11
- Molecular Weight:676.75
IUPAC Name: ((1aR,1bS,2R,4aR,4bS,8aR,9S,9aS,10aR,10bS,10cS,11bS,Z)-7-(acetoxymethyl)-2,9-dihydroxy-4-(1-methoxy-1-oxopropan-2-ylidene)-1b,10b-dimethyl-3,6-dioxo-1,1a,1b,2,3,4,4a,6,8,8a,9,9a,10,10a,10b,10c,11,11b-octadecahydrocyclopropa[4',5']cyclopenta[1',2':7,8]cycl
InChIKey: WZKZSZYDBUUHLB-IBBKUXAASA-N
SMILES: COC(/C(C)=C1[C@]2([H])[C@@]34[C@](CC5=C2[C@]([C@@]6([H])[C@]5([H])C6)([C@H](C/1=O)O)C)([H])[C@]7([C@@]8([H])[C@]([C@](O)([C@]7([H])CC3=C(C(O4)=O)COC(C)=O)COC(/C(C)=C/C)=O)([H])C8)C)=O
Biological Activity: Chlorahololide D is a potent and selective Potassium Channel blocker with an IC50 value of 2.7 μM. Chlorahololide D is a nature product that could be isolated from the whole plant of Chloranthus holostegius[1].
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Chlorahololide D | Chlorahololide D is a potent and selective Potassium Channel blocker with an IC50 value of 2.7 μM. Chlorahololide D is a nature product that could be isolated from the whole plant of Chloranthus holostegius. | |||||||||||||||||||||
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Keywords
