73215-91-5
73215-91-5
Chemical Structure
Chloranthalactone C
- CAS No.: 73215-91-5
- Formula:C17H20O4
- Molecular Weight:288.34
SMILES: C[C@]12[C@@]3([H])[C@]([C@H]([C@]1([H])CC(C(O4)=C2)=C(C)C4=O)COC(C)=O)([H])C3
Biological Activity: Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research[1][2].
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Chloranthalactone C | Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research. | |||||||||||||||||||||
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References
- [1]. Lu QQ, et al. Crystal structure and Hirshfeld analysis of (1aS,3aR,4aS,5aR)-15-acet-oxy-linden-7(11),8-trieno-12,8-lactone. Acta Crystallogr E Crystallogr Commun. 2022 May 20;78(Pt 6):642-646. [Content Brief]
- [2]. Zhou B, et al. Nanomolar Antimalarial Agents against Chloroquine-Resistant Plasmodium falciparum from Medicinal Plants and Their Structure-Activity Relationships. J Nat Prod. 2017 Jan 27;80(1):96-107. [Content Brief]
