(E/Z)-Flavokawain B
(E/Z)-Flavokawain B (compound 4) is a chalcone and nitric oxide production inhibitor with an IC50 of 6.8 μM.(E/Z)-Flavokawain B can be found in the aerial parts of Sarcandra glabra.(E/Z)-Flavokawain B inhibits lipopolysaccharide-induced nitric oxide production.
For research use only. We do not sell to patients.
- CAS No.: 76554-24-0
- Formula: C17H16O4
- Molecular Weight:284.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
19.7 μM
Compound: 21
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
|
[PMID: 31673309] |
Chemical Information
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CAS No. 76554-24-0
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Molecular Weight 284.31
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Formula C17H16O4
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SMILES
O=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=CC=C2
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Synonyms
(E/Z)-Flavokavain B
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)